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Cat. No. | Product Name | Target | Signaling Pathways |
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T68401 |
IG-105
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IG-105 is a potent microtubule inhibitor with potential anticancer activity. IG-105 inhibits microtubule assembly by binding at colchicine pocket. IG-105 shows a potent anticancer activity in vitro and in vivo and has good safety in mice. IG-105 showed a potent activity against human leukemia and solid tumors in breast, liver, prostate, lung, skin, colon, and pancreas with IC(50) values between 0.012 and 0.298 mumol/L. It was also active in drug-resistant tumor cells and not a P-glycoprotein sub... | |||
T76696 |
Onvatilimab
JNJ-61610588 |
Others | Others |
Onvatilimab (JNJ-61610588) 是一种人 IgG1κ 抗 VISTA (T 细胞激活的 V 域 Ig 抑制剂) 单克隆抗体。Onvatilimab 具有抗肿瘤活性,可用于治疗晚期头颈癌。 。 | |||
T81297 |
Renvistobart
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Renvistobart为针对[Homo sapiens(含Ig结构域及ITIM、VSIG9、VSTM3的T细胞免疫受体)]的Homo sapiens IgG1-κ型单克隆抗体。 | |||
T22856 |
IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]
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Others | Others |
IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral |
Cat. No. | Product Name | Species | Expression System |
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TMPJ-00748 |
Ig kappa Protein, Human, Recombinant (His)
Ig κ chain C region AG,Ig κ |
Human | HEK293 Cells |
Immunoglobulin Kappa is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humo... | |||
TMPJ-00824 |
Ig lambda constant 2 Protein, Human, Recombinant (His)
Ig λ constant 2 Protein, Human, Recombinant (His),M... |
Human | HEK293 Cells |
Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. IGLC2 is 105 amino acids (aa) in length. I... | |||
TMPK-00314 |
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
B7-H3,PSEC0249,PRO352, 4Ig-B7-H3,B7 homolog 3,UNQ30... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m... | |||
TMPK-00315 |
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated
4Ig-B7-H3,CD276,UNQ309,B7-H3,PRO352,PSEC0249,B7 ho... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. T... |